Our principal research focus is rooted in comprehending the physical principles of phase behavior of Intrinsically Disordered Proteins (IDPs) and their complexes with RNA and DNA, which underpin their biological functions. This compelling area of study has far-reaching implications given that IDPs account for a substantial portion (30-40%) of the eukaryotic proteome. Despite challenging the conventional protein structure-function paradigm, it is now widely accepted that these IDPs play pivotal roles in organizational, regulatory, and signaling functions within living systems. Moreover, IDPs are frequently associated with a broad array of human diseases, including neurodegeneration and cancer, further emphasizing the importance of our research.

To tackle these complex questions, our lab employs an innovative approach integrating high-resolution fluorescence microscopy, optical tweezer technology, microfluidics, cell biology, polymer theories, and computational methods. This unique combination allows us to explore and understand the intricacies of IDPs in unprecedented detail.

Beyond our scientific pursuits, we place great emphasis on fostering a supportive team environment that extends beyond the lab's physical walls. Our group thrives on collaboration, both in celebrating our successes and tackling our scientific challenges.

Whether you are a prospective student, fellow researcher, or simply an interested visitor, we invite you to explore our lab's journey as it unfolds. Our commitment to excellence in research and dedication to fostering a dynamic and inclusive team make Banerjee Lab an exciting place to be.